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Testosterone is an essential hormone produced both in men and women. Low levels of total testosterone can lead to low sex drive and reduce bone mass. Most circulating testosterone is bound to sex hormone-binding globulin (SHBG) and a small proportion exists as free hormone. Total testosterone, SHBG and free testosterone are used together to indicate to diseases of various organs such as testicles, pituitary gland (a tiny organ, the size of a pea, found at the base of your brain), thyroid, ovaries, and adrenal glands (two small glands located on the top of each kidney).

Testosterone is an essential hormone produced both in men and women. Low Free Testosterone can lead to decreased sexual function, loss of pubic hair, and loss of motivation and concentration. Most circulating testosterone is bound to sex hormone-binding globulin (SHBG) and a small proportion exists as free hormone. Total testosterone, SHBG and free testosterone are used together to indicate to diseases of various organs such as testicles, pituitary gland (a tiny organ, the size of a pea, found at the base of your brain), thyroid, ovaries, and adrenal glands (two small glands located on the top of each kidney).

Dehydroepiandrosterone (DHEA) is a hormone produced in the adrenal glands in both men and women. Adrenal glands sit above each kidney. DHEA helps produce other hormones, including testosterone and estrogen. Abnormal DHEA level is related to adrenal disease, polycystic ovary syndrome, and pituitary gland disease.

Cortisol is a main glucocorticoid which plays a critical role in your blood sugar metabolism, stress response, bone growth, blood pressure control, immune system function, and even nervous system function. Abnormal cortisol level in blood may indicate diseases of pituitary (a tiny organ sits in the base of your brain) and adrenal glands (two small glands located on the top of each kidney). Dysregulated cortisol level in your body can lead to a number of health problems such as anxiety, depression, headaches, trouble sleeping, weight gain, and heart disease.

Sex hormone binding globulin (SHBG) is a protein that is produced by the liver and binds tightly to the hormones testosterone and estradiol (an estrogen). The main function of SHBG is to transport the sex hormones within the blood stream and to target tissues, and to regulate the balance of various sex hormones in your body. A defect in SHBG production could lead to insulin resistance, type 2 diabetes, increased intra-abdominal fat deposition and an unfavorable cardiovascular risk profile. Abnormal SHBG levels are also associated with polycystic ovarian syndrome, eating disorder, thyroid dysfunction, and metabolic syndrome.