Vascular Health
Check

Member Pricing – $149.00

Non-Member Pricing – $199.00

Vascular Health Check

We’ve developed the Vascular Health Check to help people better understand their risk for heart disease or coronary event even if their lipid results and measurements such as blood pressure are not cause for concern.

  • ADMA
  • SDMA
  • Lp-PLA2

Note: Please allow apx. 10 business days for your results to appear after you have submitted your sample.

Overview | Summary | Detail

Category: SKU: 1004

Description

Click on the tests below to learn more about each one and discuss with your physician if this testing is appropriate for you to better manage your personal health or existing disease.

Vascular Health Check

Vascular Health Check

Below are the individual tests that are included in Ultimate Health Check that will show on your Prevé report in the MyPreve area. 

Vascular Health Check

 

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    ADMA

    ADMA, or asymmetric dimethylarginine, levels increase in the body from high cholesterol, atheroscerlosis and heart disease. ADMA inhibits the production of nitric oxide (NO), which is essential in the proper maintenance of endothelial cell growth in blood vessels. Endothelial cells act as a kind of bubble wrap inside our blood vessel walls protecting our blood vessels from potential damage. Increased levels of ADMA have been shown to generate an excess of free radicals, which can lead to oxidative stress and inflammation. Elevated ADMA levels are also associated with a 2.5 fold risk increase of future heart disease and are early signs of insulin resistance, the root cause of type 2 diabetes. Both diabetes and heart disease have been associated with an increased risk for Alzheimer’s disease.

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    SDMA

    SDMA, or symmetric dimethylarginine, levels increase in the body from high cholesterol, atherosclerosis and heart disease. SDMA can inhibit the production of nitric oxide (NO) through a more complicated pathway than ADMA. NO is essential in the proper maintenance of endothelial cell growth in blood vessels. Endothelial cells act as a kind of bubble wrap inside our blood vessel walls protecting our blood vessels from potential damage. Increased levels of SDMA have been shown to generate an excess of free radicals, which can lead to oxidative stress and inflammation. Elevated SDMA levels are also associated with chronic kidney disease (CKD), coronary artery disease (CAD) and diabetes. Both diabetes and heart disease have been associated with an increased risk for Alzheimer’s disease.

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    Lp-PLA2

    Lipoprotein-associated phospholipase A2 (Lp-PLA2) is produced by the body during inflammation caused by oxidative stress. It is used as an inflammatory marker of cardiovascular disease that appears to play a role in the inflammation of blood vessels and is thought to help promote atherosclerosis, coronary heart disease and stroke. Individuals with elevated Lp-PLA2 activity are twice as likely to experience a heart disease event.